Learn about Men and Miscarriage

Around a quarter of all couples will experience a miscarriage. High levels of sperm DNA damage have been shown to double the likelihood of a miscarriage occurring.

Around a quarter of all couples will experience the emotional heartache of miscarriage at some time. While many of these will be a single sporadic event, some couples will suffer repeated – or recurrent – miscarriages. Recurrent miscarriage can be caused by several factors including abnormal chromosomes in the foetus, female hormonal problems or issues with the woman’s womb. Another significant factor in recurrent miscarriage is the quality of the man’s sperm DNA.

Learn about Men and Miscarriage

Sperm DNA damage

Sperm DNA is the most important part of the sperm. It contains the genetic instructions that will makes a baby look and act like its parents. Sperm DNA can be damaged during sperm production and transport. Examen research shows that over 90% of recurrent miscarriage patients tested had sperm DNA damage above the levels found in couples who went on to have a healthy baby. This was true for couples who conceived naturally as well as those whose conceived with fertility treatment.

Sperm DNA damage can be affected by things like stress, smoking, recreational drugs, obesity and other avoidable lifestyle factors. Men can make simple lifestyle changes to improve the quality of their sperm DNA. They can reduce their sperm oxidative stress levels by making healthier choices such as eating a better diet, taking more exercise, reducing weight, stopping smoking, reducing alcohol intake and keeping their testes cool.


SpermComet® is Examen’s market leading sperm DNA test. SpermComet® measures the actual DNA damage in individual sperm making it the most sensitive sperm DNA damage test available. SpermComet® is highly predictive of male involvement in miscarriage. It can provide couples with a history of miscarriage with important information, allowing them to make informed decisions about their future pathways to starting their family.

Learn about the test

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