Extend® Double-Strand SDF Test:
The Only Test that Exclusively Detects
Double-Strand DNA Breaks

What is the Extend Test Used For?

The Extend test is particularly beneficial in the following clinical scenarios:

• Recurrent Early Pregnancy Loss (RPL): For couples experiencing multiple early miscarriages (within the first 12 weeks), the test helps determine if elevated dsDB levels in sperm are contributing to pregnancy loss.
• Surgical Sperm Retrieval (SSR) Candidates: Men being considered for SSR procedures can benefit from the Extend test to assess sperm DNA quality and its suitability for SSR prior to undertaking the surgery, thereby aiding informed decision-making for ongoing fertility treatments.

How the Extend Test Can Benefit Patients

For individuals and couples facing fertility challenges, the Extend test offers several advantages:

• Targeted Diagnostic Insights: By focusing on dsDB, the test uncovers specific DNA damage that standard semen analyses overlook, providing a clearer understanding of male fertility issues.
• Personalised Treatment Planning: Identifying the presence of dsDB allows healthcare providers to tailor interventions, potentially improving the chances of successful conception and reducing the emotional and financial strain of repeated unsuccessful ART cycles.
• Empowerment Through Knowledge: Understanding their sperm dsDB integrity enables male patients to make informed decisions about treatment options, actively participating in their fertility journey.

How the Extend Test Helps Clinicians

Healthcare professionals gain valuable insights from the Extend test, enabling them to:

• Enhanced Diagnostic Accuracy: The exclusive measurement of dsDB offers a detailed assessment of sperm DNA quality, facilitating a more precise identification of underlying fertility issues.
• Tailored Treatment Strategies: Detailed information on dsDB levels assists in selecting the most appropriate assisted reproductive techniques or other routes to parenthood to improve patient outcomes.
• Optimised Patient Journeys: With comprehensive data on sperm dsDB integrity, clinicians can provide evidence-based guidance, setting realistic expectations and outlining effective pathways to achieving successful pregnancies or alternative pathways to parenthood.